Tracing and detection coagulation necrosis induced by high intensity focused ultrasound under speckle technique

Objective To study the feasibility of utilization of speckle tracing principles to detect the incidence of coagulation necrosis caused by high intensity focused ultrasound (HIFU). Methods In order to detect the incidence of coagulation necrosis,the correlation coefficients were selected as evaluation parameters to compare the similarity of target ultrasound image before and after HIFU radiation with the speckle tracing principles,and histogenesis of coagulation necrosis was detected. Results There were 180 points of radiation,and the correct rate and error rate was 65.60% and 34.40% respectively with gray-processing software to determine histogenesis of coagulation necrosis. Taking the radiation power of 90 W for example,when the correlation coefficients was lower than 0.58,there was both incidence of coagulation necrosis and obvious gray variation; when the correlation coefficients was less than 0.75,there was no gray variation but coagulation necrosis occurred. Conclusion Speckle tracing is more sensitive than strong echoes way in the judgment of the coagulation necrosis,and the stability is very good when the image acquisition conditions keep consistent. Speckle tracing can become a new way to detect the incidence of coagulation necrosis.