Protein expression of close homologue of L1 (CHL1) is a marker for overall survival in non-small cell lung cancer (NSCLC)

Jenny Hötzel,Nathaniel Melling,Julia Muller,Adam Polonski,Gerrit Wolters-Eisfeld,Jakob R. Izbicki,Karl F. Karstens,Michael Tachezy

Protein expression of close homologue of L1 (CHL1) is a marker for overall survival in non-small cell lung cancer (NSCLC)

2019

Jenny Hötzel
Nathaniel Melling
Julia Muller
Adam Polonski
Gerrit Wolters-Eisfeld
Jakob R. Izbicki
Karl F. Karstens
Michael Tachezy

Background The cell adhesion molecule close homologue of L1 (CHL1) is a potential tumour suppressor and was recently detected in non-small cell lung cancer (NSCLC) specimens. The expression pattern, prognostic, and functional role of CHL1 in NSCLCs is unknown.

Keywords:

non-small cell lung cancer (NSCLC)
Suppressor
Pathology
CHL1
Lung cancer
Cell adhesion molecule
Cell
Protein expression
Cancer research
Biology
Adenocarcinoma
Tissue microarray
Internal medicine
Immunohistochemistry
Oncology
Survival analysis
Lymph node

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