A method for the preparation of vitamin e acetate

2011 
The invention relates to a method for preparing vitamin E acetate acetic ester. In the method, trimethyl hydroquinone and isophytol are used as raw materials, a condensation catalyst comprises concentrated sulfuric acid and coppersulfate or the concentrated sulfuric acid and zinc sulfate, and an esterifying agent is anhydrous sodium acetate, sodium borohydride and acetic anhydride. The method comprises the following steps of: preparing a reaction solvent by using the concentrated sulfuric acid and ethyl acetate, adding the trimethyl hydroquinone, the coppersulfate or the zinc sulfate and the isophytol sequentially to prepare crude vitamin E by the condensation reaction, and esterifying. By the method for preparing the vitamin E acetate acetic ester, the corrosion on equipment can be reduced, products do not have a toxic or side effect and are high in purity, the cost of wastewater treatment is low, and the total cost is also low.
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