Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis

Denny L. Cottle, Gloria M. A. Ursino, Sally Chi Ieng Ip, Lynelle Jones, Tia DiTommaso, Douglas F. Hacking, Niamh E. Mangan, Natalie A. Mellett, Katya J. Henley, Dmitri Sviridov, Claudia A. Nold-Petry, Marcel F. Nold, Peter J. Meikle, Benjamin T. Kile and Ian Smyth Department of Biochemistry and Molecular Biology, Monash University, Wellington Road, Clayton 3800, Victoria, Australia Walter and Eliza Hall Institute, 1G Royal Parade, Parkville 3052, Victoria, Australia Department of Anaesthetics, Saint Vincent’s Hospital. Melbourne, Australia Centre for Innate Immunity and Infectious Diseases, MIMR-PHI Institute of Medical Research, 27-31 Wright Street, Clayton 3168, Victoria, Australia Baker IDI Heart and Diabetes Institute, 75 Commercial Road, Melbourne 3004, Victoria, Australia Department of Medical Biology, University of Melbourne, Parkville 3010, Victoria, Australia The Ritchie Centre, MIMR-PHI Institute of Medical Research, 27-31 Wright Street, Clayton 3168, Victoria, Australia Department of Anatomy and Developmental Biology, Monash University, Wellington Road, Clayton 3800, Victoria, Australia Correspondence: E-mail: ian.smyth@monash.edu, Tel: +61 3 9902-9119; Fax: +61 3 99052500