C-reactive Protein to Albumin Ratio as a Prognostic Predictor in Larynx Cancer

Introduction: During the past decade, several inflammation-based prognostic systems have been reported in the field of clinical oncology. Recently, C-reactive protein (CRP) and albumin ratio (CAR) have showed their impact on a large variety of tumor types. The aim of this study is to evaluate the impact CAR on prognosis and 5 year survival in patients operated for larynx cancer. Methods: 118 patients operated in our center between 2010 and 2015 were eligible for retrospective analysis. We evaluated the impact of the CAR and NLR on the 5-year survival. Univariate and multivariate Cox regression analysis were performed to determine the associations of CAR. Results: The optimal cutoff level of CAR was at 0.993. A low and high CAR was assigned to 40.7% and 59.3% of patients, respectively. The 5 year survival(5yS) rates of patients with a high CAR was worse than those in the low group (79.2% vs 73.2% p