Effect of synthetic peptide fragments of β2-glycoprotein-I on the binding of antiphospholipid antibodies to cardiolipin-glycoprotein-I on the binding of antiphospholipid antibodies to cardiolipin

The synthetic fragment of β2-glycoprotein-I peptide P5 (Phe280-Ser289) maximally inhibits the binding of anticardiolipin antibodies to cardiolipin. This β2-glycoprotein-I sequence probably reacts with negatively charged phospholipids and antibodies.