O-GlcNAc-Selective-N-Acetyl-β-D-Glucosaminidase Activity and mRNA Expression in Muscle Is Related to Glucosamine-Induced Insulin Resistance

Genoveva Durán-Reyes,Dalila Pascoe-Lira,Rebeca García-Macedo,Rafael Medina-Navarro,Ana María Rosales-Torres,Marcela Vergara-Onofre,Enrique Foyo-Niembro,Margarita Gutiérrez-Rodríguez,María Trinidad Adriana García-Gutiérrez,Adán Valladares-Salgado,Jesús Kumate,Miguel A. Cruz

O-GlcNAc-Selective-N-Acetyl-β-D-Glucosaminidase Activity and mRNA Expression in Muscle Is Related to Glucosamine-Induced Insulin Resistance

2010

Genoveva Durán-Reyes
Dalila Pascoe-Lira
Rebeca García-Macedo
Rafael Medina-Navarro
Ana María Rosales-Torres
Marcela Vergara-Onofre
Enrique Foyo-Niembro
Margarita Gutiérrez-Rodríguez
María Trinidad Adriana García-Gutiérrez
Adán Valladares-Salgado
Jesús Kumate
Miguel A. Cruz

Glucosamine (GlcN)-induced insulin resistance is associated with an increase in O-linked-N-acetylglucosaminylated modified proteins (O-GlcNAcylated proteins). The role played by O-GlcNAc-selective-N-a

Keywords:

Diabetes mellitus
Insulin resistance
Glucosamine
Enzyme
Internal medicine
Endocrinology
Glucose tolerance test
Glucosaminidase
Messenger RNA
Chemistry
Biochemistry
Insulin tolerance test
n acetyl β d glucosaminidase
mrna expression

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