The Influence of Magnesium on the Electrophysiological Effects of Erythromycin in the Isolated Guinea Pig Heart

There have been several case reports that erythromycin can prolong the QT interval, resulting in torsades de pointes. As magnesium is well established in the treatment of torsades de pointes, we aimed to investigate how this trace element influences the electrophysiological effects of erythromycin.