7 Relationship between comorbidities in patients with chronic low back pain undergoing interventional pain management techniques, and patient satisfaction and clinical response

Background and Aims Response to Interventional Pain Management Techniques is often variable and unpredictable. This study aims to evaluate the association between comorbidities of 251 patients undergoing Interventional Pain Management Techniques (IPMT) for Chronic Low Back Pain (CLBP) with patient satisfaction and clinical response at 1 month after IPMT. Methods This is a sub–study of a prospective longitudinal observational study (PReTI–Back, NCT NCT04451252). Adult patients who were prescribed a IPMT were eligible. Patients who refused to participate in the study and those who had intercurrent pathology that could interfere with the evaluation of pain were excluded. Approval has been granted by the ethics committee of our hospital. Results No statistically significant differences regarding fibromyalgia, anxiety/depression, substance abuse disorder, diabetes, arthrosis, osteoporosis, rheumatic disease, obesity and other chronic pain were identified. The following findings were statistically significant. Patients with failed back surgery syndrome (FBSS) or neuropathic pain (NP)obtained a lower clinical response rate and lower percentage of patient satisfaction. Also, patients with neurogenic claudication (NC) had a lower rate of major improvement (table 1). Conclusions FBSS, NP and NC were associated with worse response to IPMT. Further investigation is needed to address the importance of comorbidities in IPMT response, so as to be taken into account when individualizing management of CLBP.