Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines.

Brittany Avin McKelvey,Timothy Gilpatrick,Yongchun Wang,Winston Timp,Christopher B. Umbricht,Martha A. Zeiger

Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines.

2020

Brittany Avin McKelvey
Timothy Gilpatrick
Yongchun Wang
Winston Timp
Christopher B. Umbricht
Martha A. Zeiger

Background: Telomerase reverse transcriptase (TERT) promoter mutations play a role in carcinogenesis and are found in both tumors and cancer cell lines. TERT promoter methylation, transcription fac...

Keywords:

Transcription (biology)
cancer cell lines
promoter methylation
Mutant
Cancer research
Medicine
Carcinogenesis
thyroid cancer cell
Endocrinology
Internal medicine
Allele
Telomerase reverse transcriptase
Transcriptional regulation
Molecular biology
Telomerase
DNA methylation
Methylation

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