Highly Active [Pd(μ‐Cl)Cl(NHC)]2 Complexes in the Mizoroki—Heck Reaction.

A series of Pd dimers bearing an N-heterocyclic carbene ligand was studied in the Mizoroki–Heck reaction. [Pd(μ-Cl)Cl(SIPr)]2 (SIPr = {N,N′-bis[2,6-(diisopropyl)phenyl]imidazolidin-2-ylidene}) was shown to be highly efficient in this cross-coupling for a range of aryl and heterocyclic bromides, with low palladium loading (20–200 ppm).