GC-MS/MS method for synchronously detecting specific nitrosamine and volatile N-nitrosamine in tobacco and tobacco products

The invention discloses a GC-MS/MS method for synchronously detecting specific nitrosamine and volatile N-nitrosamine in tobacco and tobacco products. Four kinds of nitrosamine of NNN, NAT, NAB and NNK and eight kinds of volatile N-nitrosamine of NDMA, NPYR, NPIP, NMOR, NRMA, NDEA, NDPA and NDBA are specially included. The method is characterized in that a sodium hydroxide solution is added into a tobacco sample, dichloromethane is added after uniform mixing carried out in a handholding oscillation mode, oscillation is carried out through an oscillator, anhydrous magnesium sulfate is added, the mixture is added into the oscillator to be oscillated after handholding oscillation, then, centrifugation and concentration are carried out, and finally, GC-MS/MS analysis is carried out. The method has the advantages that sample pretreatment is easy and convenient, the specific nitrosamine and volatile N-nitrosamine in the tobacco can be analyzed synchronously, batch treatment can be carried out, the measuring speed is high, the adding standard recovery rate is good, the degree of precision is high, and the technical support can be provided for accurately assessing the safety risks of the specific nitrosamine and volatile N-nitrosamine in the tobacco and tobacco products.