Electron microscopic verification of adenocarcinoma of the cardioesophageal area

: Normal gastric and esophageal cardiac glands as well as proper esophageal glands were studied electron-microscopically. Cardiac gastric and esophageal glands were found to differ by chief cells available in the gastric glands and greater amounts of endocrine cells registered in the esophageal glands. The evidence can provide grounds for electron microscopic verification of cardioesophageal adenocarcinoma permitting the pathologist to rest upon the presence of cells resembling those of proper gastric glands and epigastric fossa. In addition, it can promote specification of the morphologic type of adenogenic esophageal cancer comprising squamous epithelial component and secretory granules typical of proper esophageal glands.