Evaluation of Anticancer Activity of Vitex Leucoxylon

This article presents a review of evaluation of anticancer effect of methanol extract of the leaves of  vitex leucoxylon linn (verbenaceae)  on EAC induced solid tumour. The study sampled 30 mice, devided into 5 groups 96 in each). Ascites tumour was  developed by administering  Ehrlich ascites cells (0.1ml/10gm body wt of mouse,i.p) from 1x10 6 cells.. The mice were treated with steroids of Vitex leucoxylon  and 5-fluro uracil which serves as standard. The several changes of antitumor potential of steroidal extract of Vitex leucoxylon were accessed. Steroids of leaves of Vitex leucoxylon treated group showed significant decrease in Total number of cells, Percentage viability, Tumour volume of Ehrlich Ascites Carcinoma in mice. From result, it was concluded that steroids of leaves of Vitex leucoxylon shows anti-tumour activity.