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LYMPHOME GASTRIQUE DU MALT

2013 
It is the most frequent location of the primary digestive tract lymphoma , originally from the lymphoid tissue of the digestive tract or MALT. We distinguishe two types: the marginal zone lymphoma of malt and diffuse large B cell lymphoma .The clinical symptoms are not specific and the diagnosis depend on the biopsy results. The disease staging is systematic looking for remote associated nodal or visceral involvement. The role of the Helicobacter pylori recently implied in the genesis of these malignant lymphomas reopened all the debates including the therapeutic. The discovery in the latter years of anatomopathological, immunohistochemical and molecular diagnosis tools and also new efficient therapeutic strategies contributed to improve the prognosis. The treatment is based on the helicobacter pylori eradication. The marginal zone lymphoma treatment is consensual and well codified, chemotherapy and /or radiotherapy can be proposed if no improvement. For the diffuse large B cell lymphoma the chemotherapy is the standard treatment associated or not with surgery or radiotherapy. The addition of the CD 20 antibody can improve the results.
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