Selective chlorination method

The invention provides a selective chlorination method which comprises the following step of: mixing a compound with a structural formula (I), a basic compound, water and a chlorinating regent under the condition of a catalyst for chlorination reaction to obtain a compound with a structural formula (II), wherein the catalyst is an amide compound or a pyridine compound, and the chlorinating regent is an oxydol hydrochloric acid system or sodium hypochlorite. Compared with the prior art, firstly, the selective chlorination method provided by the invention adopts the oxydol hydrochloric acid system or the sodium hypochlorite as the chlorinating regent and carries out chlorination by adopting a water-phase chlorination method, thereby enhancing the selectivity of the chlorination reaction; the selective chlorination method provided by the invention can obtain the qualified product through separation, thereby achieving the safety of a chlorination method and reducing the pollution on the environment and the corrosion on equipment; and secondly, the selective chlorination method provided by the invention increases the yield of the chlorination reaction by adding the added amide compound or pyridine compound as the catalyst.