The Efficacy and Value of Proton MR Spectroscopy In Evaluating the Brain Tumours

Our aim was to evaluate the usefulness of proton MR spectroscopy (H-MRS) in categorizing the brain tumours. Multivoxel imaging (MV-MRS) was performed to 33 patients with intra-cranial mass lesions at Philips 1.5 T Achieva MR unit. The brain tumours are classified to; low-high grade glial neoplasms, menengiomas and metastasis. Cho/NAA, Cho/Cr, Cho/MI ratios are calculated for all tumour groups and according to these metabolite ratios by using statistical analysis. We tried to show the differences between groups and tried to categorize them. All three ratios are highest in GBM group, Cho/NAA- Cho/MI ratios are lowest in low-grade gliomas, Cho/Cr ratio is lowest in menengiomas. Metastasis also have strong elevation of Cho resonances and all three ratios are also high in this group. As a conclusion, MV-MRS is a useful tool, provides important informations for the analysis of the brain tumours of different types and for grading glial neoplasms with 97% sensitivity and 87.9% specificity.