Apolipoprotein E ε4 Allele Is Associated with Increased Atrophy in Progressive Mild Cognitive Impairment: A Voxel-Based Morphometric Study

Anne Hämäläinen,Marta Grau-Olivares,Susanna Tervo,Eini Niskanen,Corina Pennanen,J. Huuskonen,Miia Kivipelto,Tuomo Hänninen,Mia Tapiola,Matti Vanhanen,Merja Hallikainen,Eeva-Liisa Helkala,Aulikki Nissinen,Ritva Vanninen,H. Soininen

Apolipoprotein E ε4 Allele Is Associated with Increased Atrophy in Progressive Mild Cognitive Impairment: A Voxel-Based Morphometric Study

2008

Anne Hämäläinen
Marta Grau-Olivares
Susanna Tervo
Eini Niskanen
Corina Pennanen
J. Huuskonen
Miia Kivipelto
Tuomo Hänninen
Mia Tapiola
Matti Vanhanen
Merja Hallikainen
Eeva-Liisa Helkala
Aulikki Nissinen
Ritva Vanninen
H. Soininen

Background: The apolipoprotein E (APOE) E4 allele is a risk factor for Alzheimer’s disease. Earlier studies have shown differences in brain structure according to the APOE [

Keywords:

Pathology
Risk factor
Voxel-based morphometry
Apolipoprotein E
Voxel
Diabetes mellitus
Disease
Allele
Biology
Atrophy

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