158 移行上皮細胞に認められる核溝について(第41回日本臨床細胞学会秋期大会)

We report a case of chromophobe renal cell carcinoma in a 39-year-old woman. The squash cytological specimen showed tumor cell clusters composed of large-sized polygonal cells with a low nucleocytoplasmic ratio. The cytoplasm was characteristically cloudy and reticular or eosinophilic granular. Occasionally, a perinuclear halo was visible. The nuclei were spherical and contained small nucleoli. The unique clinicopathological and molecular biological characteristics of chromophobe renal cell carcinoma make cytology a very useful tool for its correct diagnosis.