Derivatives use anticonvulsants to treat cluster headaches.

The use of a compound for the manufacture of a medicament for treating cluster headaches in a subject, said compound having the formula I wherein X is CH2 or oxygen; R1 is hydrogen or C1 - C4; and R2, R3, R4 and R5 are independently hydrogen or C1 - C3 and, when X is CH2, R4 and R5 may be alkene groups joined to form a benzene ring and, when X is oxygen, R2 and R3 and / or R4 and R5 together may be a methylenedioxy group of the following formula (II): wherein R6 and R7 are the same or different and are hydrogen, C1 - C3 or R6 and R7 together with the carbon to which they are attached are joined to form a cyclopentyl or cyclohexyl ring.