The thrombolytic therapy of Urokinase in 45 patients with central venous double-lumen catheter thrombosis

Objective: To investigate the effective method of the double-lumen central venous catheter thrombosis.Methods: 45 cases of renal failure,indwelling central venous double-lumen catheter in patients with central venous catheter thrombosis was established,the first with Urokinase 100 000 U+saline 10 ml dubbed concentration 10 000 U/ml Urokinase solution to 1 ml syringe in thrombosis slow side of intraductal injection of Urokinase solution 1.0 ml,10 min after the injection of Urokinase solution of 0.3～0.5 ml,another 10 min injection of Urokinase solution 0.3～0.5 ml,after 10 min with 10 ml syringe to retain suction catheter,immediately following saline drip a few minutes,if the dialysis catheter barrier can repeat these steps.Results: 45 cases of patients treated with this method in 43 cases of ductal patency,catheter embolization in 2 cases because of time greater than 3 days,thrombolytic treatment failure,changed other parts of the re-tube.Conclusion: The early treatment of catheter method has been applied thrombolytic recanalization rate and reduce the suffering of patients with re-catheterization and economic burden.