Clinical analysis on acute ST-segment elevation myocardial infarction in patients with normal coronary angiography

Objective To investigate the morbidity,the clinical characteristics and follow-up outcomes of acute ST-segment elevation myocardial infarction( STEMI) with normal coronary angiography ( CAG) . Methods The clinical characteristics and results of CAG and some correlated risk factors of 648 patients with STEMI enrolled from March 2006 to October 2010 and during the follow up were analysed. Results The patients with STEMI and normal CAG accounted for 56 / 648( 8. 6% ) ,most of whom were young patients and smokers. Most patients had strenuous exertional working,and free of angina pectoris, hypertension,diabetes mellitus and hyperlipidemia ( P 0. 01) . The clinical follow-up was completed for 51 patients and during the follow-up period,no acute myocardial infarction or cardiogenic death occurred. Conclusions STEMI might happen in patients with normal coronary arteries. The coronary spasm or acute thrombosis and auto-thromobolysis on the basis of coronary endothelium lesion may occur in them. The follow-up shows some patients have recurrent angina even though they continue the use of statins and calcium antagonists.