Chromatin modification of Notch targets in olfactory receptor neuron diversification
2012
This study shows a new molecular mechanism governing olfactory receptor neuron (ORN) subtype diversification from a shared precursor cell. Selection of ORNs in Drosophila is mediated by Notch signaling. Chromatin modifications directed to specific genes targeted by Notch modify the responses to this signal and diversify ORN identity and circuitry.
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