Cerebral vasomotor reactivity predicts the development of acute stroke in patients with internal carotid artery stenosis
2018
Abstract Objective To investigate the relationship between cerebral vasomotor reactivity (VMR) and acute stroke in patients with internal carotid artery stenosis. Methods 54 patients with internal carotid artery stenosis were enrolled. VMR was calculated by transcranial Doppler monitoring of the velocity of blood flow. 3-Dimensional dynamic contrast enhanced magnetic resonance angiography was used to detect stenosis, and diffusion weighted imaging was used to detect infarction. Results VMR value was significantly lower in patients with carotid artery stenosis than in control group ( T = 3.112, P = 0.002), and significantly lower in patients with aortic atherosclerotic stroke than in non-infarct group ( T = 10.930, P = 0.000). However, VMR value was significantly higher in patients with new-onset small-artery occlusion stroke than in non-infarction group ( T = −2.538, P = 0.013). Scatter plots showed that aortic atherosclerotic stroke occurred mainly in patients with severe internal carotid artery stenosis, and VMR value in cerebral artery significantly decreased. Conclusion Decreased VMR value is an important prognostic factor for the occurrence of aortic atherosclerotic stroke, and can be used as a reference for preoperative hemodynamic evaluation in patients with internal carotid artery stenosis.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
13
References
5
Citations
NaN
KQI