BMI1 promotes steroidogenesis through maintaining redox homeostasis in mouse MLTC-1 and primary Leydig cells.

Tingting Gao,Meng Lin,Binbin Shao,Qiao Zhou,Yufeng Wang,Xia Chen,Dan Zhao,Xiuliang Dai,Cong Shen,Hongbo Cheng,Shenmin Yang,Hong Li,Bo Zheng,Xingming Zhong,Jun Yu,Li Chen,Xiaoyan Huang

BMI1 promotes steroidogenesis through maintaining redox homeostasis in mouse MLTC-1 and primary Leydig cells.

2020

Tingting Gao
Meng Lin
Binbin Shao
Qiao Zhou
Yufeng Wang
Xia Chen
Dan Zhao
Xiuliang Dai
Cong Shen
Hongbo Cheng
Shenmin Yang
Hong Li
Bo Zheng
Xingming Zhong
Jun Yu
Li Chen
Xiaoyan Huang

In males, aging is accompanied by decline in serum testosterone levels due to impairment of testicular Leydig cells. The polycomb protein BMI1 has recently been identified as an anti-aging factor. ...

Keywords:

redox homeostasis
Cell biology
BMI1
serum testosterone
Biology
Oxidative stress

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