Oleanane Saponins from Rhizome of Anemone raddeana

Two new oleanolic acid-type triterpenoid saponins, raddeanosides R22 and R23 (1 and 2, resp.), together with four known saponins were isolated from the rhizome of Anemone raddeanaRegel. The structures of the new compounds were elucidated as oleanolic acid 3-O-β-D-glucopyranosyl(12)[β-D-glucopyranosyl(14)]-α-L-arabinopyranoside (1) and oleanolic acid 3-O-α-L-arabinopyranosyl(13)-α-L-rhamnopyranosyl(12)[β-D-glucopyranosyl(14)]-α-L-arabinopyranoside (2). The four known compounds were identified as oleanolic acid 3-O-α-L-arabinopyranoside (3), oleanolic acid 3-O-β-D-glucopyranosyl(14)-α-L-arabinopyranoside (4), hederasaponin B (5), and hederacholchiside E (6) on the basis of chemical and spectral evidences. Compound 4 is reported for the first time from the Anemone genus, while the other three known compounds have been already found in this plant.