A promising source of anticancer drug from fungal secondary metabolite

Abstract Secondary metabolites from fungi have been purified, characterized, and further modified in their moieties as anticancer agents. In the last few decades, fungal metabolites have become an important role in cancer drug discovery, resulting in a large number of therapeutic agents. Several studies have identified fungal metabolites as promising anticancer agents, and they have been investigated for their efficacy by using various types of cell lines, animal models, and clinical trials for cancer. This chapter discusses fungal metabolites and their efficacy as well as the toxicity of synthetic derivatives. Further, we discuss the efficacy of metabolites in animal models as well as clinical trials on fungal metabolites as anticancer agents.