Pantoprazole sodium freeze-drying pharmaceutical composition for injection and preparation method thereof

The invention provides a pantoprazole sodium freeze-drying pharmaceutical composition for injection and a preparation method thereof. Effective components of the pantoprazole sodium freeze-drying pharmaceutical composition includes, by weight, 1 part of pantoprazole sodium, 0.5-1.1 parts of excipient, 0.01-0.04 part of calcium disodium edetate, 0.1-0.3 part of sodium caprylate and the balance activated carbon for needles, wherein the volume of the activated carbon accounts for 0.01-1% of the total preparation volume. The pantoprazole sodium freeze-drying pharmaceutical composition and the preparation method thereof have the advantages that through prescription and preparation process optimization, common metachromatism during clinical compatibility as well as clinical medication fracture risks, which are warned by FDA (food and drug administration) of the United States and possibly caused by proton pump inhibitors, can be solved, patients' fracture risks caused by calcium ion loss during medication are reduced, and medication safety is higher.