method for selecting at least one screen for mutations, its application to a method for rapid identification of alleles of polymorphic systems and device for its implementation óoeuvre.

at least a screen selection methods of mutations from a set of allelic sequences of a polymorphic gene and rapid identification of alleles of polymorphic genes, nucleotide probes derived from said screens of changes, in particular consisting in database and device for implementing said methods. The method for the identification of alleles comprises: (a) selecting all or part of a known consensus sequence of said polymorphic gene; (B) creating a mutation matrix corresponding sequences of known alleles; (C) identifying sequences indistinguishable by pairwise comparison (alleles having the same profile mutations in the selected sequence in (a)) and exclusion of one of the members of said pairs; (E) Identification and enumeration of mutations or mutations mandatory said marker alleles, that is to say those which are necessary and sufficient to distinguish two alleles otherwise identical (set O mandatory mutations); and (f) obtaining said / said minimum sieves of mutations, comprising at least the required mutations of step (e); and (g) selecting, among the screens selected in step (f) said mutation screens selection method, the screen mutations most suitable for the production of oligonucleotide probes capable of being used for differentiation of all alleles; (H) a suitable hybridization of an allele X to identify oligonucleotide probes selected from the / mutations sieves established in steps (a) to (g); and (i) identification of the allele X by detecting said / said hybrids possibly formed during step (h).