Estimation of attenuation maps from scatter and photopeak window single photon-emission computed tomographic images of technetium 99m-labeled sestamibi

Background In single photon-emission computed tomographic imaging of the chest, nonuniform attenuation correction requires use of a patient-specific attenuation map. The aim of this study was to determine whether an estimate of the regions of the lungs and nonpulmonary tissues of the chest could be obtained by segmenting the photopeak and Compton scatter window images in a phantom and in patients to estimate patient-specific attenuation maps.