A physiological model of the hunger response in humans

The hunger response in humans has been simulated in an quantitative temporal physiological model using the Center for Research and Education in Aging Language (CREAL). CREAL is a language that can be used to describe biological systems from a macro to a molecular scale. The simulation of the hunger response shows the concentration of compounds throughout the model, during a 24 hour period. The release of orexin, which modulates the human hunger response is simulated with respect to insulin, leptin, and gherkin, this is achieved by modeling the neural pathways linking the gut, the arcuate nucleus, and the paraventricular nucleus.