원저 : 지각과 도인이 고지방식이로 유발된 비만 흰쥐에 미치는 영향

Objectives : We had experiment with Aurantii Fructus Immaturus and Persicae Semen in order to find cure effects for an obesity. Methods : We fed control group rats high fat diet and administered normal saline for 8 weeks. And we fed experimental group rats high fat diet and administered extract of Aurantii Fructus Immaturus and Persicae Semen for 8weeks. Results : The changes of the body weights in Aurantii Fructiis Immaturus group showed a significant decrease at 5, 7 and 8 weeks in comparison with control group. Hut in Persicae Semen group didn`t show a significant decrease in comparison with control group. The serum total cholesterol, free fatty acid, lipid, phospholipid level in Aurantii Fructus Immaturus group showed a significant decrease in comparison with control group. The serum level in Persicae Semen group didn`t show significant change in comparison with control group. The average size of the epididymal fat cells of the rats in Aurantii Fructus Immaturus group showtd a significant decrease in comparison with control group. but in Persicae Semen group didn`t show a significant decrease in comparison with control group. The area `.4 of the fat drops in hepatic lobule of rats in Aurantii Fructus Immaturus and Persicae Semen grou:~ showed a decrease in comparison with control group. but these results were not significant. Conclusion : Results of our research in this paper show that Aurantii Fructus Immaturus might have cure an obesity.