Ultrastructural characteristics of the parenchymatous and stromal components and their interrelationship in breast cancer

: The results of the clinico-anatomical analysis of 228 autopsy cases of pancreonecrosis identified during 20 years are presented. The authors put forward their own classification of pancreonecrosis based on the degree of the pancreas affection: diffuse small-focal, large-focal and subtotal with the distinguishing their haemorrhagic and ischemic (fat) types. Early (up to 7 days) and late (more than 7 days) complications with typical clinico-morphological manifestations are distinguished depending upon the time when the death occurred. The main cause of "early" death was a pancreatogenic shock with the morphological manifestations of the enzymatic polyserositis, acute pulmonary thrombo-hemorrhagic complications and degenerative alterations in the parenchymatous organs. Late complications of pancreonecrosis were manifested by a purulent-necrotic destruction of the pancreas and retroperitoneal fat with the abscesses, purulent peritonitis, inner fistulas of the alimentary canal organs and erosive hemorrhages.