Renal TLR4 mRNA Expression Correlates with Inflammatory Marker MCP-1 and Profibrotic Molecule TGF-β1 in Patients with Chronic Kidney Disease

Julia Lepenies,K.S. Eardley,Tina Kienitz,Martin Hewison,Thomas Ihl,Paul M. Stewart,Paul Cockwell,Marcus Quinkler

Renal TLR4 mRNA Expression Correlates with Inflammatory Marker MCP-1 and Profibrotic Molecule TGF-β1 in Patients with Chronic Kidney Disease

2011

Julia Lepenies
K.S. Eardley
Tina Kienitz
Martin Hewison
Thomas Ihl
Paul M. Stewart
Paul Cockwell
Marcus Quinkler

Background: Toll-like receptor-4 (TLR4) has been implicated in the pathogenesis of different renal diseases in rodent models. However, in human kidney disease, TLR4 expression and r

Keywords:

Diabetes mellitus
Medicine
Intensive care medicine
Renal function
Pathogenesis
TLR4
Interleukin 6
Kidney disease
Transforming growth factor
Endocrinology
Glomerular basement membrane
Internal medicine
Proteinuria
Disease
Immunology

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