Severe headache in primary Sjögren’s syndrome treated with intrathecal rituximab

Severe and treatment‐resistant headache sometimes occurs in patients with systemic lupus erythematosus, so called lupus‐headache.It is defined as a persistent headache that “may be migrainous, but must be nonresponsive to narcotic analgesia”.1 We report a case of similar severe and disabling headache in a patient with primary Sjogren's syndrome (pSS) that was successfully treated with intrathecal rituximab.