The response of renal cortical adenine nucleotides to different flush-out solutions

Changes in energy metabolism of canine renal cortex were investigated immediately after nephrectomy and following flushout with two solutions. Even a brief period of ischaemic produced a sharp fall in adenine nucleotide concentration: further fall was prevented by flushout with cold Ringer’s solution and some restoration of nucleotides was achieved by flushing with a modified Collins’ solution.