CHIRAL AUXILIARY-PROMOTED ASYMMETRIC NUCLEOPHILE ADDITIONS TO ARENE-MANGANESE TRICARBONYL COMPLEXES

Abstract Addition of a range of nucleophiles to arene-manganese tricarbonyl complexes, carrying a chiral non-racemic 2,5-dimethylpyrrolidine substituent, results in diastereomeric excesses of up to 94%. Dependence of the level of asymmetric induction on reactivity and steric bulk of the nucleophile is observed, revealing a rather complex set of controlling factors for the reaction.