[Application of vestibular function examination battery in the staging of vestibular function in Meniere's disease].

Objective:To investigate the staging of vestibular organ damage in Meniere's disease, based on the vestibular function examination battery. Methods:Thirty-nine patients, clinically diagnosed as unilateral Meniere's disease, underwent audiologic test and vestibular function examination battery, including ocular vestibular evoked myogenic potential（oVEMP）, cervical vestibular evoke myogenic potential（cVEMP）, and caloric tests. Based on the results of the vestibular function examination battery, the vestibular function was divided into 4 stages. StageⅠ: oVEMP, cVEMP, and caloric tests were normal; stage Ⅱ: any one test of the three examinations was abnormal; stage Ⅲ: two of the three examinations were abnormal; Stage Ⅳ: All the three examinations were abnormal. Results:According to the vestibular function staging strategy in this study, patients in stage Ⅰ, Ⅱ, Ⅲ, Ⅳ were 7.7%（3/39）, 30.8%（12/39）, 33.3%（13/39）, 28.2%（11/39） respectively in the 39 Meniere's disease patients. However, according to the current clinical staging strategy of Meniere's disease, patients of stage1, 2, 3, 4 were 20.5%（8/39）, 43.6%（17/39）, 28.2%（11/39）, and 7.7%（3/39） respectively. 37.5%（3/8） patients in stage 1 and 64.7%（11/17） patients in stage 2 had two or more abnormal vestibular organs. While all the patients in stage 4 had abnormal semicircular canals, utricle, and saccule. The stage of vestibular function was correlated with the distribution of current clinical staging strategy of Meniere's disease（P<0.05）. Conclusion:The combination of oVEMP, cVEMP and caloric tests can divide the vestibular function into four stages, which can be used as a supplement to the traditional vestibular evaluation and clinical staging based on audiology in Meniere's disease.