A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control

Elena Tondini,Tsolere Arakelian,Koen Oosterhuis,Marcel Camps,Suzanne van Duikeren,Wanda Han,Ramon Arens,Gerben Zondag,Jeroen van Bergen,Ferry Ossendorp

A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control

2019

Elena Tondini
Tsolere Arakelian
Koen Oosterhuis
Marcel Camps
Suzanne van Duikeren
Wanda Han
Ramon Arens
Gerben Zondag
Jeroen van Bergen
Ferry Ossendorp

ABSTRACTThe combination of immune-stimulating strategies has the potency to improve immunotherapy of cancer. Vaccination against neoepitopes derived from patient tumor material can generate tumor-s...

Keywords:

Potency
DNA vaccination
Cancer
Blockade
Cancer immunotherapy
Medicine
Cancer research
Immunology
Immunotherapy
T cell
Vaccination
pd 1 blockade

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