Enfermedad orbitaria relacionada con Ig-G4

espanolCaso clinico Presentamos el caso de una mujer de 64 anos con tumefaccion palpebral, dacrioadenitis bilateral y exoftalmos, e historia de rinitis cronica y asma bronquial. Se evidencio aumento de IgG4 serica y se realizo biopsia incisional de glandulas lagrimales que demostro fibrosis e infiltrado linfoplasmocitario con celulas productoras de IgG4. Discusion El compromiso orbitario en enfermedad relacionada con IgG4 es frecuente. La dacrioadenitis bilateral es la manifestacion mas comun. La histopatologia es esencial para el diagnostico de la enfermedad y excluir malignidad. EnglishCase report The case is presented of a 64-year-old woman with bilateral palpebral swelling and dacryoadenitis, exophthalmos, and a history of chronic rhinitis and asthma. An increase in serum IgG4 was observed, and an incisional biopsy of lacrimal glands was performed, which showed fibrosis and a lymphoplasmacytic infiltrate with IgG4 producing cells. Discussion Orbital involvement in IgG4-related disease is frequent. Bilateral dacryoadenitis is the most common manifestation. Histopathology is essential for the diagnosis and to exclude malignancy