Protective and therapeutic effects of milrinone on acoustic trauma in rat cochlea

Seyit Mehmet Ceylan,Erdal Uysal,Serdar Altınay,Efe Sezgin,Nagihan Bilal,Emine Petekkaya,Mehmet Dokur,Mahmut Alper Kanmaz,Mustafa Emre Gulbagci

Protective and therapeutic effects of milrinone on acoustic trauma in rat cochlea

2019

Seyit Mehmet Ceylan
Erdal Uysal
Serdar Altınay
Efe Sezgin
Nagihan Bilal
Emine Petekkaya
Mehmet Dokur
Mahmut Alper Kanmaz
Mustafa Emre Gulbagci

Objective The aim of this study was to investigate the potential protective and therapeutic effects of milrinone, a specific phosphodiesterase (PDE) III inhibitor, on acoustic trauma-induced cochlear injury and apoptosis.

Keywords:

Anesthesia
Surgery
Milrinone
Acoustic trauma
Medicine
Cochlea
Therapeutic effect
Inflammation
Edema
Phosphodiesterase
Apoptosis

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