Rapid and sensitive UPLC-MS/MS method for the determination of etodolac in small-volume rat plasma: Application to rat real samples

Mehmet Emrah Yaman,Omer Faruk Kocak,Alptug Atila,Yucel Kadioglu,Busra Diyarbakir,Zekai Halici

Rapid and sensitive UPLC-MS/MS method for the determination of etodolac in small-volume rat plasma: Application to rat real samples

2018

Mehmet Emrah Yaman
Omer Faruk Kocak
Alptug Atila
Yucel Kadioglu
Busra Diyarbakir
Zekai Halici

AbstractA rapid, simple, and sensitive UPLC-MS/MS method was developed and validated for the determination of etodolac in rat plasma using flurbiprofen as an internal standard (IS). Etodolac and IS...

Keywords:

Analytical chemistry
Etodolac
High-performance liquid chromatography
Chemistry
Chromatography
Solvent
Tandem mass spectrometry
Calibration curve
Ammonium formate
Selected reaction monitoring
Flurbiprofen
Electrospray ionization

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