Metformin hydrochloride sustained-release enteric-coated pellets and its preparation method

The invention belongs to the field of medicinal preparations, and discloses a metformin hydrochloride enteric-coated sustained-release pellet and a preparation method thereof. The preparation method comprises the steps of preparing a metformin hydrochloride active pellet core, coating a sustained-release layer and coating an enteric layer. The preparation method can be used for preparing the metformin hydrochloride enteric-coated sustained-release pellet which has attractive appearance, good fluidity and high bioavailability, can be slowly released in intestinal tracts and is mild in action and low in adverse reaction incidence by screening and optimizing the process.