Intratumoural (IT) evolutionary landscape of high-risk prostate cancer and outcome: The PROGENY (PROstate cancer GENomic heterogeneitY) study of genomic and immune parameters.

Anuradha Jayaram,Gerald Goh,Bihani Yoshana Kularatne,Jasmin V. Waterhouse,Yaalini Shanmugabavan,Andrew Rowan,Yien Ning Sophia Wong,Alex Freeman,Ayse U. Akarca,Javier Herrero,Rachel Rosenthal,Nicholas McGranahan,Michelle Hung,Mark Emberton,Gerhardt Attard,Sergio A. Quezada,Teresa Marafioti,Hashim U. Ahmed,Charles Swanton,Mark Linch

Intratumoural (IT) evolutionary landscape of high-risk prostate cancer and outcome: The PROGENY (PROstate cancer GENomic heterogeneitY) study of genomic and immune parameters.

2020

e17500Background: IT heterogeneity (ITH) is well recognised in prostate cancer (PC), but its role in high-risk disease and patient outcomes are uncertain. Methods: This was a prospective, single-ar...

Keywords:

Oncology
Evolutionary landscape
Immune system
Pathology
Prostate cancer
Internal medicine
Medicine

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