Intraspinal anesthetic and preparation method and application thereof

The invention discloses an intraspinal anesthetic and a preparation method and an application thereof. The intraspinal anesthetic comprises dexmedetomidine, epinephrine, betamethasone and water for injection. The preparation method comprises the following steps: (1) after the betamethasone and the epinephrine are mixed and 50% of water for injection of the full dose are added, uniformly mixing; (2) after the dexmedetomidine is mixed in a mixing solution in step (1), adding the water for injection to full dose, and uniformly mixing; (3) filtrating and sterilizing the mixing solution in step (2) to obtain the intraspinal anesthetic. The invention further provides the application of the intraspinal anesthetic in the preparation of the intraspinal anesthetic. According to the intraspinal anesthetic provided by the invention, the neurovirulent effect caused by using local anesthetics to the intraspinal anesthesia can be prevented; furthermore, the intraspinal anesthetic has the effects of analgesia, calm, muscle relaxation and adverse areflexia and shiver prevention, can evade the adverse effects of the vein use and can be used for special patients.