CMV Colitis Presenting as Neoplastic Lesions with Life-Threatening Bleeding in an Immunocompetent Patient

An elderly woman with multiple medical problems developed cytomegalovirus (CMV) colitis following a prolonged hospitalization. She presented life–threatening colonic bleeding mimicking a neoplastic process while the final diagnosis was CMV colitis. This is an uncommon presentation of CMV colitis in an immunocompetent patient needing a high index of suspicion to proceed early with proper diagnosis and therapy.