Radical Retropubic Prostatectomy: A Review of 8 Years of Experience

Objectives: Different modalities for treating prostate cancer are evolving worldwide. Radical prostatectomy is still ranking on top of the list for organ- confined disease. This study was conducted out to describe the indications, surgical technique, complications and outcome of radical retropubic prostatectomy for prostate cancer over an 8- year period at Prince Hussein Center of Urology and Organ Transplant, King Hussein Medical Center. Methods: Between August 1999 and June 2007, a total of 81 patients (age range 50-68 years) underwent radical retropubic prostatectomy for organ confined prostate cancer (stage T1a-T2c) based on Prostate Specific Antigen values, histopathology reports (Gleason Score 4-7) and negative metastatic work up. Followup of these patients ranged between 1 and 7 years. The medical records of these patients were reviewed, and analyzed regarding indications, surgical technique, complications, and outcome. Results: None of the patients had pelvic lymph node involvement, and surgery accomplished in 2.5-3.5 hours. Estimated blood loss was between 500 and 2000ml. Early continence, within 4 weeks after surgery, was achieved in 51/81 (62.9%) and in 98.7 % after one year. Potency within 1 year was achieved in 42 patients (51.8%), but with medications this number reached 52 (64%). Margin positive histopathology reports were seen in 12 patients (14.8%) warranting further treatment with either radiotherapy or hormonal therapy. Mortality rate in the study group was 2.5 % as a result of disease progression and dissemination.