ANTIOXIDANT ACTIVITY OF HUMAN MIXED SALIVA IN NORM

It is known that the monitoring of superoxide dismutase and catalase activity allows to assess the level of influence of environmental situation in particular chemical factors of ecosystem on public health. "Oxidative stress" is one of the mechanisms of environmental influence on human organism. Considering complex character of catalase and superoxide dismutase activity change interpretation of the obtained results can be difficult, thus it is more effective to use integrated indices in particular, antioxidant activity. The aim of the study was to develop approaches to assessing the severity of "oxidative stress" by determining the activity of antioxidant enzymes and antioxidant activity of human saliva and study variations of these parameters in norm. It is shown that activity of individual antioxidant enzymes varies even during the day, and therefore the interpretation of these values і s difficult. Antioxidant activity can be a most promising indicator for assessing the intensity of the "oxidative stress" of biological fluids, such as saliva. Method of determining of antioxidant activity saliva is picked up using 2,6-dichlorophenolindophenol. Temporal and physiological characteristics are determined for the dynamics of saliva antioxidant activity in norm, the stability of this parameter is shown, taking into account age and gender characteristics.