Effect of pancreatic DNAse on Bacillus subtilis multiplication depending on the physiological state of the culture

: The effect of pancreatic DNAase on the growth of Bacillus subtilis, the synthesis of DNA, RNA and protein in the cells was studied as a function of their physiological state. The cells were found to be sensitive to the action of DNAase at the end of the linear growth phase, which coincided with their transition into the competence state and with their ability to adsorb the enzyme on the cell surface.