Morphological aspects of particle translocation in vivo following ingestion of the yeast Saccharomyces boulardii.

AbstractParticle translocation in vivo was studied in mice using the non-pathogenic yeast Saccharomyces boulardii (SB). Seven day old BALB/c mice were given either saline (control) or 1.5 g/Kg SB (every six hours, up to 48 hours), by intubation, and killed by decapitation 48 hours post-treatment. Light and scanning electron microscopy (SEM) examination of specimens prepared from the middle intestine revealed the presence of yeast inclusions localised in the cytoplasm of enterocytes.